"Marina, Lauren and Jason "

The McIntyre Lab is a part of the Department of Molecular Genetics and Microbiology at the University of Florida. We are developing new methods to help analyze large amounts of data and understand complex problems in genetics and evolution. Similar to Systems Biology, we are largely concerned with whole systems of "omic" data from genomic to proteomic, and we apply statistical theory to extend our research across DNA, RNA and proteins and model the relationships that result in the phenotype. This area of research has also been referred to as 'genetical genomics'.

We study populations that have available genetic information, from structured populations to natural populations. In the past, we have used everything from Drosophila and Staphylococcus aureus to arabidopsis, maize and trees. Beyond examining single populations for data, we study the relationship between structured populations and natural populations.

We also study the technologies and procedures that we use in our experiments so that we can understand their limitations and ensure that our data is accurate to an acceptable margin of error. We test and develop QA/QC procedures that we integrate into future experimental design. Specifically, we have worked on rater agreement, phenotyping, and expression data.